Hyaluronic acid (HA) fillers — like Juvederm® or Restylane® — are gel-like injectables made of hyaluronic acid, a substance naturally found in your skin. They instantly add volume, smooth wrinkles, and enhance features like lips or cheeks. Biostimulators — such as Sculptra® or Radiesse® — work differently: instead of filling instantly, they stimulate your body’s own collagen production over time, gradually improving skin firmness and volume for longer-lasting, natural-looking results.

HA fillers are commonly used to plump lips, lift cheeks, contour the jawline, fill nasolabial folds, marionette lines, and under-eye hollows. Biostimulators are popular for restoring volume in larger areas like the cheeks and temples, smoothing deep wrinkles, and improving skin laxity. Some biostimulators, like Radiesse®, can also rejuvenate hands. Your provider will recommend the best option based on your goals and skin condition.

When performed by a licensed, experienced injector — such as a board-certified dermatologist or aesthetic doctor — both HA fillers and biostimulators are considered safe and FDA-approved. Side effects like temporary swelling, bruising, or redness are common but typically mild. Serious risks, like vascular complications, are rare but highlight why it’s crucial to choose an expert injector who understands facial anatomy and advanced injection techniques.

HA fillers provide immediate results that typically last 6–18 months, depending on the area treated, the product used, and your body’s metabolism. Biostimulators take longer — results develop gradually over 2–3 months as new collagen forms, with improvements lasting up to 2 years or more. Many patients appreciate combining both treatments for instant volume with long-term collagen stimulation.

Both treatments are non-surgical and usually take 30–60 minutes. Your injector may apply a numbing cream to ensure comfort. After treatment, mild swelling or bruising is normal and usually resolves within days. Follow any aftercare instructions, like avoiding strenuous exercise, excessive sun, or touching the treated area for 24–48 hours, to minimize side effects and optimize results.